Enfocus PitStop Version 13 Update 1 brings a lot of new features like improvements for adding objects to pages (including step and repeat), add grommets for large format printing, preflight restriction to a contour (e.g. die line), a new profile to fix PDFs created by Office applications. The new version officially supports MacOS X version 10.11 (El Capitan) and Windows 10.
IMHO the most important improvement is the possibility to restrict checks and fixes to the area inside or outside a specific contour (e.g. die line):